Jonathan (Yoni) Leor is a Professor of Cardiology at the Tel-Aviv University and Director of the Tamman Cardiovascular Research Institute, the Neufeld Cardiovascular Research Institute, and the Center of Regenerative Medicine at the Sheba Medical Center, Tel-Hashomer, Israel.Leor�s lab aims to target the reparative pathways, specifically inflammation and stem cells, to optimize cardiac repair and regeneration, using different platforms such as nano-medicine and reprogramming. Today, a special effort is being placed on the development of theranostic (therapy + diagnosis) nanotechnology to improve therapies to combat heart disease.

Nili is a PhD researcher and the lab manager. Her research focused on the therapeutic potential of human mesenchymal stem cells (MSCs) for cardiovascular repair.

Olga is a Ph.D. student, her research focuses on the role of extracellular vesicles from epicardial fat in the pathogenesis and treatment of atrial fibrillation.

Itai is a Ph.D. student. His research focuses on the pleiotropic role of Osteopontin during myocardial regeneration and repair.

Yeshai is a PhD student. His research focuses on CRISPR-Cas9-based gene editing of human mesenchymal stromal cells to improve the outcome of cell therapy. He aims to to provide a new strategy to enhance MSC-based cell therapy to improve cardiac remodeling and function in patients who suffer from heart failure.

Rafael is an MD PhD student. His research focuses on monocyte- derived extra cellular vesicles and their role in primary hypertension and hypertensive heart disease. He aims to find new therapeutic targets and potential biomarkers for patients at risk for future cardiovascular disease. He works in collaboration with Prof. Ehud Grossman�s lab.

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La-Paz was a PHD student, her research focused on the role of macrophages and SIRT6 in myocardial aging.

Razan was an MSc student, her research foucuses on fibro adipogenic progenitors cells and their role in cardiac regeneration.

Olga was a PhD student. Her research focused on the role of macrophages in inflammation process. Using the model of atherosclerotic ApoE KO mice we're trying to modulate inflammation with different nano-agents, such as� E-Selectin marked nano-probes conjugated to dexamethasone, liposomes and cerium-coated Iron nano-particles.

Dahlia is a PhD researcher and an MD intern. Her research focused on the role of macrophage derived Wnt signaling in cardiac repair.

Tal is a PhD researcher and an MD intern. Her research focused on using innovative models to explore the mechanisms underlining regeneration in murine neonatal hearts.

PhD Researcher

Clinical Fellow.
Uri's PhD research aimed to explore the mechanisms underlying age-related deterioration of vascular and cardiac function and identify novel therapeutic targets. Toward this aim he studied the role of the longevity gene Sirtuin 6 in the development of cardiovascular disease, regeneration and heart failure by using genetically engineered mice models in collaboration with Prof. Haim Cohen lab (BIU). Furthermore, he studied the role of IL-13 receptor ?1 in the development of atherosclerosis and cardiac fibrosis, in collaboration with Dr. Ariel Munitz (TAU) lab.

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