Leor Lab
Jonathan Leor, MD,
Professor of Cardiology Principal Investigator
E-mail: leorj@post.tau.ac.il
Jonathan (Yoni) Leor is a Professor of Cardiology at the Tel-Aviv University and Director of the Tamman Cardiovascular Research Institute, the Neufeld Cardiovascular Research Institute, and the Center of Regenerative Medicine at the Sheba Medical Center, Tel-Hashomer, Israel.Leor’s lab aims to target the reparative pathways, specifically inflammation and stem cells, to optimize cardiac repair and regeneration, using different platforms such as nano-medicine and reprogramming. Today, a special effort is being placed on the development of theranostic (therapy + diagnosis) nanotechnology to improve therapies to combat heart disease.
Olga Teper, PhD stutent
E-mail: olgashai@yahoo.ca
Olga is a Ph.D. student, her research focuses on the role of extracellular vesicles from epicardial fat in the pathogenesis and treatment of atrial fibrillation.
Yeshai Schary, PhD student
E-mail: yeshai.schary@mail.tau.ac.il
Phone: +972-3-530-8409
Yeshai is a PhD student. His research focuses on CRISPR-Cas9-based gene editing of human mesenchymal stromal cells to improve the outcome of cell therapy. He aims to to provide a new strategy to enhance MSC-based cell therapy to improve cardiac remodeling and function in patients who suffer from heart failure.
Rafael Y. Brzezinski MD PhD student
E-mail: rafibrz5@gmail.com
Phone: +972-3-530-8481
Rafael is an MD PhD student. His research focuses on monocyte- derived extra cellular vesicles and their role in primary hypertension and hypertensive heart disease. He aims to find new therapeutic targets and potential biomarkers for patients at risk for future cardiovascular disease. He works in collaboration with Prof. Ehud Grossman’s lab.
Nir Lewis, MD PhD student
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Daria Lendengolts, DVM
E-mail: lendengolts@gmail.com
Ayala Aharon
Administrative assistant
Tel: 972-3-530-3523
Fax: 972-3-5351139
E-mail: Ayala.Aharon@sheba.health.gov.il
Hila bar
Administrative assistant
Tel: 972-3-530-2614
Fax: 972-3-5351139
E-mail: Hila.bar@sheba.health.gov.il
La-Paz Levin-Kotler PhD student
E-mail: lapazlevin@gmail.com
Phone: +972-3-530-8410
La-Paz is a PHD student, her research focuses on the role of macrophages and SIRT6 in myocardial aging.
Olga Yarenchyk PhD student
E-mail: ola.yar@gmail.com
Phone: +972-3-530-8409
Olga is a PhD student. Her research is focused on the role of macrophages in inflammation process. Using the model of atherosclerotic ApoE KO mice we're trying to modulate inflammation with different nano-agents, such as E-Selectin marked nano-probes conjugated to dexamethasone, liposomes and cerium-coated Iron nano-particles.
Razan Younis, MSc student
E-mail: razanyounis@mail.tau.ac.il
Phone: +972-3-530-8409
Razan is a MSc student, her research foucuses on fibro adipogenic progenitors cells and their role in cardiac regeneration.
Uri Amit, Clinical Fellow
E-mail: uri.amit.mail@gmail.com
Phone: +972-3-530-8409
Uri's research aims to explore the mechanisms underlying age-related deterioration of vascular and cardiac function and identify novel therapeutic targets. Toward this aim he studies the role of the longevity gene Sirtuin 6 in the development of cardiovascular disease, regeneration and heart failure by using genetically engineered mice models in collaboration with Prof. Haim Cohen lab (BIU). Furthermore, he studies the role of IL-13 receptor α1 in the development of atherosclerosis and cardiac fibrosis, in collaboration with Dr. Ariel Munitz (TAU) lab.